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Manufacturer Supply Cilengitide 98% white powder CAS NO.188968-51-6

Cilengitide  CAS NO:188968-51-6
Cilengitide is a cyclic pentapeptide peptide that competes for the arginine-glycine-aspartate (RGD) peptide sequence. Regulates integrin-ligand binding. Cilengitide selectively and effectively restrain alpha v beta 3 beta and alpha v 5 integrin combined with matrix proteins, such as Vitronectin, Fibronectin, Fibrinogen, vonWillebrandFactor, Osteopontin, and others. The 10μMCilengiChemicalbooktide completely inhibits the adhesion of BAE, BME and HUVE cells to Vitronectin and Fibronectin. Cilengitide acts in vitro on BAE cells pretreated with FGF-2(or VEGF-A) of three-dimensional collagen and blood fibrin gel to inhibit angiogenesis with IC50 of 15 and 8μM, and 4 and 3μM, respectively. Cilengitide inhibits cell proliferation, induces endothelial cell apoptosis, and induces human endothelial precursor cell differentiation.


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Product Name Cilengitide
CAS 188968-51-6
molecular formula C27H40N8O7
molecular weight 588.66
density 1.41±0.1 g/cm3(Predicted)
solubility ≥29.43 mg/mL in DMSO; ≥22.56 mg/mL in H2O
Acidity coefficient (pKa) 4.01±0.10(Predicted)
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SaiWanTe (Shanghai) New Material Technology Co.,Ltd  . is a professional R & D and production of plastic particles, yarn, food additives, foreign trade company. Cosmetics, etc., own their own factories,Therefore, we have been sincerely recognized by many customers. In the face of so many achievements, we are still striving to make breakthroughs in this industry. Our aim is to produce the best products, with professional service and attitude to make every customer satisfied. We look forward to working with you to build a win-win relationship with you. Please rest assured that we will give you satisfaction.

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